منابع مشابه
Co-existent chronic lymphatic leukaemia with polycythaemia vera.
A patient presenting with chronic lymphocytic leukaemia and iron deficiency anaemia who, following oral iron therapy, developed the clinical and pathological features of polycythaemia vera is reported. The relationship between these two diseases when co-existing is discussed.
متن کاملPolycythaemia rubra vera and hairy cell leukaemia in the same patient: studies on the spleen.
The first association of polycythaemia rubra vera (PRV) and hairy cell leukaemia (HCL) is reported. The secretion by spleen cells in short term culture of IfGlambda to the exclusion kappa demonstrated that despite aberrant surface marker studies the HCL was a monoclonal tumour of B cells. Chromosomal studies on splenic cells were not able to demonstrate the common clonal origin of the two tumours.
متن کاملSmoking, drinking, and polycythaemia.
The mean packed cell volume is higher in the smoking population than in non-smokers.'' Chronic hypoxaemia, from whatever cause, tends to cause a rise in the packed cell volume.4 The obvious temptation is to invoke hypoxaemia, resulting from lung disease induced by smoking, to explain the high values found in smokers-but is this apparently straightforward explanation correct? The increase in pac...
متن کاملAcute leukaemia after hydroxyurea therapy in polycythaemia vera and allied disorders: prospective study of efficacy and leukaemogenicity with therapeutic implications.
Fifty consecutive patients, 30 of whom had polycythaemia vera (PV), 10 essential thrombocythaemia (ET), and 10 myelofibrosis (MF), entered a long-term prospective study of hydroxyurea (HU) therapy. The indication for treatment was mainly thrombocytosis or symptomatic splenomegaly. Control of erythrocytosis and thrombocytosis was achieved in 70% of the patients. Continuous maintenance treatment ...
متن کاملUnderstanding and treating cytopenia through mathematical modeling.
Here, we briefly review how the study of dynamic hematological diseases with mathematical modeling tools has led to a better understanding of the origin of some types of neutropenia and thrombocytopenia and to improved treatment strategies. In addition, we have briefly discussed how these models suggest improved ways to minimize and/or treat cytopenia induced by chemotherapy.
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ژورنال
عنوان ژورنال: BMJ
سال: 1954
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.4877.1484